| Assay ID | Title | Year | Journal | Article |
|---|
| AID1745847 | CMV-Luciferase Counterscreen for Inhibitors of ATXN expression | | | |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745849 | Viability Counterscreen for CMV-Luciferase Assay of Inhibitors of ATXN expression | | | |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745846 | Firefly Luciferase Counterscreen for Inhibitors of ATXN expression | | | |
| AID1745850 | Viability Counterscreen for Confirmatory qHTS for Inhibitors of ATXN expression | | | |
| AID1745848 | Confirmatory qHTS for Inhibitors of ATXN expression | | | |
| AID1447403 | Antagonist activity at human TRPC7 receptor expressed in HEK293 cells assessed as channel desensitization up to 30 uM in presence of 0.1 mM Ca2+ by whole cell patch-clamp method | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1578756 | Agonist activity at mouse TRPC4 expressed in HEK293 cells coexpressing M5 receptor assessed as induction of TRPC4-mediated calcium influx by fluorescence method | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17
| Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. |
| AID1447397 | Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium level by Fluo-4-AM dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447388 | Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level at 33 uM measured for 2.5 mins by Fluo-8-AM dye based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447402 | Agonist activity at human TRPC7 receptor expressed in HEK293 cells assessed as induction of channel current in presence of 0.1 mM Ca2+ by whole cell patch-clamp method | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447375 | Inhibition of mouse TRPM8 expressed in HEK293 cells assessed as decrease in methanol-evoked increase in intracellular calcium level at 22 uM preincubated for 2 mins followed by methanol addition measured for 2.5 mins by Fluo8-AM dye-based fluorescence ass | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447372 | Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447392 | Agonist activity at human TRPM5 expressed in HEK293 cells assessed as induction of membrane depolarization at 33 uM measured for 2.5 mins by FLIPR membrane potential dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447386 | Agonist activity at human TRPC5 expressed in HEK293 cells assessed as induction of membrane depolarization at 33 uM measured for 2.5 mins by FLIPR membrane potential dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447373 | Agonist activity at human TRPC3 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins by Fluo-8-AM dye based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447382 | Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in membrane depolarization measured for 2.5 mins in presence of 2 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447394 | Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as induction of membrane potential depolarization measured for 2.5 mins by FLIPR assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447383 | Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 mM Ca2+ by Fluo8-AM dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447391 | Agonist activity at human TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level at 33 uM measured for 2.5 mins by Fluo-8-AM dye based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447396 | Induction of intracellular calcium level in HEK293 cells at 30 uM measured for 2.5 mins by Fluo-4-AM dye based FLIPR assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447381 | Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by whole cell patch-clamp method | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447389 | Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level at 33 uM measured for 2.5 mins by Fluo-8-AM dye based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447370 | Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium level measured for 2.5 mins by Fluo-8-AM dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447401 | Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of channel current at 10 uM measured for 2.5 mins in presence of 0.5 mM Ca2+ by whole cell patch-clamp method | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447385 | Agonist activity at mouse TRPC4beta expressed in HEK293 cells co-expressing MOR assessed as induction of membrane depolarization at 33 uM measured for 2.5 mins by FLIPR membrane potential dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447400 | Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 2 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447399 | Antagonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as channel desensitization at 20 to 100 uM at +80 mV in presence of 0.1 mM Ca2+ by whole cell patch-clamp method | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447390 | Agonist activity at mouse TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level at 33 uM measured for 2.5 mins by Fluo-8-AM dye based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447387 | Agonist activity at mouse TRPM8 expressed in HEK293 cells assessed as increase in intracellular calcium level at 33 uM measured for 2.5 mins by Fluo-8-AM dye based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447371 | Antagonist activity at mouse TRPC4beta expressed in HEK293 cells co-expressing MOR decrease in DAMGO-evoked intracellular calcium level by Fluo-8-AM dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447398 | Agonist activity at mouse TRPC4beta expressed in HEK293 cells co-expressing MOR assessed as increase in intracellular calcium level at 33 uM measured for 2.5 mins by Fluo-8-AM dye-based fluorescence assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| AID1447395 | Induction of membrane potential depolarization in HEK293 cells measured for 2.5 mins by FLIPR assay | 2017 | Journal of medicinal chemistry, 06-08, Volume: 60, Issue:11
| Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |